Found 77 articles for: "Leon H. Kircik"
Efficacy of Topical Botanical Treatment of Children With Mild to Moderate Atopic Dermatitis
October 2019 | Volume 18 | Issue 10 | Original Article | 1038 | Copyright © October 2019
Objective: The study was conducted to determine the efficacy of the botanical combination incorporated in Kamedis Eczema Therapy Cream (the test product) for children with mild to mod...
Read MoreAnti-Inflammatory Dose Doxycycline Plus Adapalene 0.3% and Benzoyl Peroxide 2.5% Gel for Severe Acne
September 2019 | Volume 18 | Issue 9 | Original Article | 924 | Copyright © September 2019
Acne is primarily an inflammatory disease. Anti-inflammatory dose doxycycline (40mg: 30mg immediate release and 10mg delayed release beads) is approved for the treatment of rosacea but w...
Read MoreValidation of Botanical Treatment Efficiency for Adults and Children Suffering from Mild to Moderate Atopic Dermatitis
June 2019 | Volume 18 | Issue 6 | Original Article | 557 | Copyright © June 2019
Objective: The study was conducted to determine the efficiency of the botanicals combination incorporated in the Kamedis Eczema Therapy Cream (the tested product) for adults and child...
Read MoreActinic Keratosis: Current Therapies and Insights Into New Treatments
May 2019 | Volume 18 | Issue 5 | Supplement Individual Articles | 161 | Copyright © May 2019
Actinic keratosis (AK) develops on chronically sun-exposed skin and constitutes one of the most common diseases ...
Read MoreAddressing the Challenges of Treating Actinic Keratosis
May 2019 | Volume 18 | Issue 5 | Supplement Individual Articles | 160 | Copyright © May 2019
Actinic keratosis (AK) represents one of the most common diagnoses in our dermatology practices. The incidence of AK lesions continues to rise, along with that of non-melanoma skin cancers. Numerous r...
Read MoreMatrix Revisited: Innovative Approach for Tretinoin
April 2019 | Volume 18 | Issue 4 | Department | 146 | Copyright © April 2019
The history of tretinoin and its use in dermatology is a testament both to the drug’s well-established efficacy and its potential to cause skin irritation. Over more than four decades, the drug ...
Read MorePolymeric Emulsion Technology Applied to Tretinoin
April 2019 | Volume 18 | Issue 4 | Supplement Individual Articles | 148 | Copyright © April 2019
The Microsponge Delivery System (MDS) for Tretinoin: A First Attempt at Reducing Irritation The Microsponge Delivery System (MDS) is a controlled drug delivery system that encapsulates the active drug...
Read MoreTretinoin Formulation: From Microsponges to Polymeric Emulsion
April 2019 | Volume 18 | Issue 4 | Supplement Individual Articles | 147 | Copyright © April 2019
The history of tretinoin and its use in dermatology is a testament both to the drug’s well-established efficacy and its potential to cause skin irritation. Over more than four decades, the drug ...
Read MoreThe Effect of Calcipotriene-Betamethasone Dipropionate Aerosol Foam versus Vehicle on Target Lesions in Moderate Severity Plaque Psoriasis: Focus on Elbows and Knees
April 2019 | Volume 18 | Issue 4 | Original Article | 358 | Copyright © April 2019
Calcipotriene 0.005%, a vitamin D analog, plus betamethasone dipropionate 0.064%, a high potency topical corticosteroid, are combined in an aerosol foam formulation proven to be effective and safe us...
Read MoreUse of Apremilast in Patients Who Are Dissatisfied With Stable Maintenance Topical Therapy
April 2019 | Volume 18 | Issue 4 | Original Article | 336 | Copyright © April 2019
OBJECTIVE: To explore the impact of adding apremilast to a regimen of topical corticosteroids in patients with moderate plaque-type psoriasis.
RESEARCH DESIGN AND METHODS: This was an open...
Read MoreTopical Treatment for the Management of Atopic Dermatitis
February 2019 | Volume 18 | Issue 2 | Supplement Individual Articles | 112 | Copyright © February 2019
Atopic dermatitis affects up to 20% of children and continues to increase in prevalence. Effective disease control is aimed at decreasing symptoms and reducing the frequency of flares, which may be co...
Read MoreManagement of Atopic Dermatitis
February 2019 | Volume 18 | Issue 2 | Supplement Individual Articles | 111 | Copyright © February 2019
Atopic Dermatitis (AD) is estimated to affect 15-20% of children and remains a major health consideration for pediatricians and dermatologists.1 Over the past three decades, studies have shown an incr...
Read MoreVehicles Always Matter
February 2019 | Volume 18 | Issue 2 | Supplement Individual Articles | 99 | Copyright © February 2019
It has been said that the best treatment for a given patient is the one that the patient will actually use. The comment, often spoken with humor, actually underscores several important aspects of derm...
Read MoreNovel Tretinoin 0.05% Lotion for the Once-daily Treatment of Moderate-to-Severe Acne Vulgaris in an Adult and Adolescent Female Population
February 2019 | Volume 18 | Issue 2 | Original Article | 178 | Copyright © February 2019
BACKGROUND: Acne vulgaris (acne) is a common dermatological condition typically associated with adolescents, affecting about 85% of young people. However, it is also prevalent and persistent into adul...
Read MoreTreatment of Moderate Acne Vulgaris in Fitzpatrick Skin Type V or VI: Efficacy and Tolerability of Fixed Combination Clindamycin Phosphate 1.2%/Benzoyl Peroxide 3.75% Gel
October 2018 | Volume 17 | Issue 10 | Original Article | 1107 | Copyright © October 2018
BACKGROUND: Acne vulgaris (acne) is the most common skin disease in patients who have darker skin with most frequent sequelae of post inflammatory hyperpigmentation (PIH). METHODS: Open label study...
Read MoreAssessing the Potential Role for Topical Melatonin in an Antiaging Skin Regimen
September 2018 | Volume 17 | Issue 9 | Original Article | 966 | Copyright © September 2018
Background: Melatonin is an endogenous hormone commonly associated with regulation of sleep. However, over the last two decades, research has elucidated a range of effects associated with the compound...
Read MoreWhat Lies Beneath the Face Value of a BOX WARNING: A Deeper Look at Brodalumab
August 2018 | Volume 17 | Issue 8 | Supplement Individual Articles | 29 | Copyright © August 2018
Brodalumab, a fully human antibody of the interleukin-17 receptor, is highly effective in the treatment of moderate-to-severe plaque psoriasis. However, based on safety signals identified in clinical ...
Read MoreDepression? It's the Disease NOT the Drug
August 2018 | Volume 17 | Issue 8 | Supplement Individual Articles | 28 | Copyright © August 2018
Research into the immunopathological mechanisms of plaque psoriasis has produced increasingly targeted biologic therapies. The specificity of these agents allows for high rates of efficacy and decreas...
Read MoreThe Practice of Compounding, Associated Compounding Regulations, and the Impact on Dermatologists
July 2018 | Volume 17 | Issue 7 | Supplement Individual Articles | 17 | Copyright © July 2018
Medication compounding gained national attention in the fall of 2012 after contaminated compounded medications produced in the New England Compounding Center infected 800 people with fungal meningitis...
Read MoreYes to Appropriate Compounding, No to Illegal Compounding
July 2018 | Volume 17 | Issue 7 | Supplement Individual Articles | 15 | Copyright © July 2018
Dermatology is often described as a “visual” specialty. While it is true that many of our diagnoses can be made based on a relatively quick recognition of morphology, such a characterization of ou...
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